The Retatrutide 30mg Pen (300 clicks at 0.1 mg) is the flagship release in the Remy Peptides retatrutide line. Batch RETP002 was sent to Janoshik Analytical — an independent EU-based peptide testing lab — and returned at 99.262% HPLC purity. This page summarises the report, the testing method, and what the result means for research use. The full Janoshik PDF lives at /coa/retp002/.
Batch Facts
- Product
- Retatrutide 30mg Pen (flagship release)
- Batch number
RETP002- Molecule
- Retatrutide (LY-3437943), CAS 2381089-83-2
- Purity (HPLC)
- 99.262%
- Test method
- HPLC (High-Performance Liquid Chromatography), reverse-phase
- Laboratory
- Janoshik Analytical — EU, independent third-party
- Analysis date
- 4 November 2025
- Format
- Pre-filled 300-click pen, 0.1 mg per click
- Storage
- 2–8°C, cold-chain shipping
The Test
The Janoshik panel for RETP002 was a reverse-phase HPLC assay — the analytical standard for quantifying purity of synthetic peptides. The retatrutide fraction is separated from peptide-related impurities (truncated sequences, deletion variants, synthesis byproducts) on a C18 stationary phase, then quantified against a reference retention time for the parent peptide (LY-3437943, CAS 2381089-83-2). The reported 99.262% figure is the area-under-the-curve percentage for the parent peak, normalised against the sum of all peptide-related peaks in the chromatogram.
HPLC does not detect non-peptide content — water, salts, residual organic solvents from synthesis, or endotoxin. For the Retatrutide vial line (batch RET-20-V-2604-001) Remy publishes a fuller Janoshik panel including residual TFA, heavy metals (As, Cd, Pb, Hg), and bacterial endotoxin (LAL). The 30mg pen ships pre-formulated and pH-balanced rather than as a lyophilized solid, so the relevant verification is HPLC purity of the dissolved peptide.
What This Means For Researchers
Retatrutide is a triple-receptor agonist — it engages GIP, GLP-1, and glucagon receptors with a single molecule. Triple-agonist potency is highly sensitive to sequence integrity: any truncation or deletion variant in the chain alters receptor binding for at least one of the three pathways, which makes HPLC purity verification meaningful, not cosmetic. The published Eli Lilly Phase 3 TRIUMPH-4 trial (28.7% mean weight loss at the 12mg dose) was conducted with reference-grade material; in-vitro research that aims to compare results to published trial data needs a comparable parent-peak fraction to be on the same baseline.
At 99.262% HPLC, batch RETP002 sits at the upper end of the 95–99% range that public peptide-purity references (GenScript, IonPeptide, Proto Peptide) cite as standard for research-grade peptides. The other 0.738% is peptide-related material, not contamination by a different molecular entity.
The Full Report
Full HPLC purity report from Janoshik Analytical for batch RETP002.
Frequently Asked
What is the HPLC purity of the Retatrutide 30mg Pen?
RETP002. Analysis date 4 November 2025. The full Janoshik report is published at /coa/retp002/.
Who tested the Retatrutide 30mg Pen COA?
How can I verify the Retatrutide 30mg Pen batch independently?
RETP002 is mirrored at /janoshik-analytical-coa.pdf and the image version at /remediumtestresults.webp. The verification walkthrough at how to verify a Janoshik COA explains how to cross-check the report against the Janoshik server using the task number and verification key printed on the report.